Product Name :MGME1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Mitochondrial genome maintenance exonuclease 1: Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endonuclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of MGME1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C20orf72; DDK1; Mitochondrial genome maintenance exonuclease 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human MGME1.
Modification :Unmodification
