Product Name :TMEM9 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Proton-transporting V-type ATPase complex assembly regulator TMEM9: Transmembrane protein that binds to and facilitates the assembly of lysosomal proton-transporting V-type ATPase (v-ATPase), resulting in enhanced lysosomal acidification and trafficking . By bringing the v-ATPase accessory protein ATP6AP2 and the v-ATPase subunit ATP6V0D1 together, allows v-ATPase complex formation and activation . TMEM9-controlled vesicular acidification induces hyperactivation of Wnt/beta-catenin signaling, involved in development, tissue homeostasis and tissue regeneration, through lysosomal degradation of adenomatous polyposis coli/APC . In the liver, involved in hepatic regeneration
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TMEM9 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DERP4; Transmembrane protein 9; Dermal papilla-derived protein 4
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TMEM9.
Modification :Unmodification
