Product Name :PACS2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Phosphofurin acidic cluster sorting protein 2: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PACS2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0602; PACS1L; Phosphofurin acidic cluster sorting protein 2; PACS-2; PACS1-like protein
Immunogen :A synthetic peptide encompassing a sequence within the center region of human PACS2.
Modification :Unmodification
