Product Name :AREL1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Apoptosis-resistant E3 ubiquitin protein ligase 1: E3 ubiquitin-protein ligase that catalyzes 'Lys-11'- or 'Lys-33'-linked polyubiquitin chains, with some preference for 'Lys-33' linkages . E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Ubiquitinates SEPTIN4, DIABLO/SMAC and HTRA2 in vitro . Modulates pulmonary inflammation by targeting SOCS2 for ubiquitination and subsequent degradation by the proteasome
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of AREL1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0317; Apoptosis-resistant E3 ubiquitin protein ligase 1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human AREL1.
Modification :Unmodification
