Product Name :TELO2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Telomere length regulation protein TEL2 homolog: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TELO2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0683; Telomere length regulation protein TEL2 homolog; Protein clk-2 homolog; hCLK2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TELO2.
Modification :Unmodification
