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NCKAP1L polyclonal antibody

货号: BS34183

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS34183

Product Name :NCKAP1L polyclonal antibody

Swiss-Prot :P55160

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Nck-associated protein 1-like: Essential hematopoietic-specific regulator of the actin cytoskeleton (Probable). Controls lymphocyte development, activation, proliferation and homeostasis, erythrocyte membrane stability, as well as phagocytosis and migration by neutrophils and macrophages . Component of the WAVE2 complex which signals downstream of RAC to stimulate F-actin polymerization. Required for stabilization and/or translation of the WAVE2 complex proteins in hematopoietic cells (By similarity). Within the WAVE2 complex, enables the cortical actin network to restrain excessive degranulation and granule release by T-cells . Required for efficient T-lymphocyte and neutrophil migration . Exhibits complex cycles of activation and inhibition to generate waves of propagating the assembly with actin . Also involved in mechanisms WAVE-independent to regulate myosin and actin polymerization during neutrophil chemotaxi...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of NCKAP1L protein

BiowMW :~128 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HEM1; Nck-associated protein 1-like; Hematopoietic protein 1; Membrane-associated protein HEM-1

Immunogen :A synthetic peptide encompassing a sequence within the center region of human NCKAP1L.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of KLF4 expression in recombincant protein (A) whole cell lysates.

免疫沉淀（IP）