Product Name :IGKV4-1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Immunoglobulin kappa variable 4-1: V segment of the variable domain of immunoglobulins light chain that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of IGKV4-1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Immunoglobulin kappa variable 4-1; B3, IGKV41
Immunogen :A synthetic peptide encompassing a sequence within the center region of human IGKV4-1.
Modification :Unmodification
