Product Name :LRIT3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3: Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells (By similarity). Required for normal transmission of a light-evoked stimulus from the cone photoreceptor cells to the ON-bipolar cells and ON-ganglion cells in the inner retina . Required in retinal ON-bipolar cells for normal localization of the cation channel TRPM1 at dendrite tips (By similarity). Seems to play a specific role in synaptic contacts made by ON-bipolar cells with cone photoreceptor pedicles (By similarity). May also have a role in cone synapse formation (By similarity). Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi . Could be a regulator of the FGFRs
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of LRIT3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human LRIT3.
Modification :Unmodification
