Product Name :GAL3ST3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Galactose-3-O-sulfotransferase 3: Catalyzes the transfer of a sulfate group from 3'-phosphoadenylyl sulfate (PAPS) to the C-3 hydroxyl group of terminal non-reducing beta-1,4-linked galactose residues in both N-glycans and O-glycans . It acts efficiently on type 2 chains (Gal-beta-1,4-GlcNAc-R) found in N-glycans and core 2-branched O-glycans (Gal-beta-1,4-GlcNAc-beta-1,6(Gal-beta-1,3)GalNAc-R) . In contrast, it shows poor activity on type 1 chains (Gal-beta-1,3-GlcNAc-R) and intermediate activity on core 1 structures (Gal-beta-1,3-GalNAc-R) . Participates in the glycoconjugates sulfation namely the 3'-sulfated Lewis X epitope (Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc), by sulfating N-acetyllactosamine (Gal-beta-1,4-GlcNAc) at the 3' position; then the resulting modification is fucosylated by FUT5
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of GAL3ST3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Galactose-3-O-sulfotransferase 3; Gal3ST-3; Beta-galactose-3-O-sulfotransferase 3; Gal3ST3; Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human GAL3ST3.
Modification :Unmodification
