Product Name :KLHL40 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Kelch-like protein 40: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development . The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex (By similarity). Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination; the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KLHL40 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KBTBD5; SRYP; Kelch-like protein 40; Kelch repeat and BTB domain-containing protein 5; Sarcosynapsin
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KLHL40.
Modification :Unmodification
