Product Name :OSBPL11 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Oxysterol-binding protein-related protein 11: Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage . Weakly binds 25-hydroxycholesterol . Interacts with OSBPL9 to function as lipid transfer proteins . Together they form a heterodimer that localizes at the ER-trans-Golgi membrane contact sites, and exchanges phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine, PS) for phosphatidylinositol-4-phosphate (1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate), PI(4)P) between the two organelles, a step that is critical for sphingomyelin synthesis in the Golgi complex
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of OSBPL11 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ORP11; OSBP12; Oxysterol-binding protein-related protein 11; ORP-11; OSBP-related protein 11
Immunogen :A synthetic peptide encompassing a sequence within the center region of human OSBPL11.
Modification :Unmodification
