Product Name :SNX33 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Sorting nexin-33: Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SNX33 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :SH3PX3; SH3PXD3C; SNX30; Sorting nexin-33; SH3 and PX domain-containing protein 3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SNX33.
Modification :Unmodification