Product Name :XKR8 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :XK-related protein 8: Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface . Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment . Required for the clearance of apoptotic cells, such as engulfment of apoptotic germ cells by Sertoli cells, clearance of senescent neutrophils or regulation of bipolar cell numbers in the retina (By similarity). In the hippocampus, phosphatidylserine exposure also acts as a specific 'eat-me' marker for axon pruning during brain development (By similarity). Has no effect on calcium-induced exposure of phosphatidylserine . Promotes myoblast differentiation and survival
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of XKR8 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :XRG8; XK-related protein 8; hXkr8
Immunogen :A synthetic peptide encompassing a sequence within the center region of human XKR8.
Modification :Unmodification
