Product Name :ARFIP2 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Arfaptin-2: Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network . May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 . Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site . Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria . In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ARFIP2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :POR1; Arfaptin-2; ADP-ribosylation factor-interacting protein 2; Partner of RAC1; Protein POR1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ARFIP2.
Modification :Unmodification
