Product Name :KBTBD4 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Kelch repeat and BTB domain-containing protein 4: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex which targets CoREST corepressor complex components RCOR1, KDM1A/LSD1 and HDAC2 for proteasomal degradation . RCOR1 is likely to be the primary target while degradation of KDM1A and HDAC2 is likely due to their association with RCOR1 . Also targets RCOR3, MIER2 and MIER3 for proteasomal degradation as well as associated proteins ZNF217 and RREB1 . Degradation is dependent on the presence of an ELM2 domain in the target proteins
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KBTBD4 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BKLHD4; Kelch repeat and BTB domain-containing protein 4; BTB and kelch domain-containing protein 4
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KBTBD4.
Modification :Unmodification
