Product Name :ARPIN polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Arpin: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ARPIN protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C15orf38; Arpin; Arp2/3 inhibition protein
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human ARPIN.
Modification :Unmodification