Product Name :ZDHHC12 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates . Has a palmitoyltransferase activity toward gephyrin/GPHN, regulating its clustering at synapses and its function in gamma-aminobutyric acid receptor clustering (By similarity). Thereby, indirectly regulates GABAergic synaptic transmission (By similarity). Negatively regulates NLRP3-driven inflammation. Catalyzes NLRP3 palmitoylation, leading to its degradation via the chaperone-mediated autophagy (CMA) process
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ZDHHC12 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ZNF400; Probable palmitoyltransferase ZDHHC12; Zinc finger DHHC domain-containing protein 12; DHHC-12; Zinc finger protein 400
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ZDHHC12.
Modification :Unmodification
