Product Name :COQ2 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :4-hydroxybenzoate polyprenyltransferase, mitochondrial: Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis . Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl donor (such as all-trans-decaprenyl diphosphate) . The length of the polyprenyl side chain varies depending on the species, in humans, the side chain is comprised of 10 isoprenyls (decaprenyl) producing CoQ10 (also known as ubiquinone), whereas rodents predominantly generate CoQ9 . However, this specificity is not complete, human tissues have low amounts of CoQ9 and rodent organs contain some CoQ10 . Plays a central role in the biosynthesis of CoQ10 . CoQ10 is a vital molecule that transports electrons from mitochondrial respiratory chain complexes . CoQs also function as cofactors for uncoupling protein and play a role as regulators of the extracellularly-induced ceramide-dependent apoptotic pathway . Regulates...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of COQ2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CL640; 4-hydroxybenzoate polyprenyltransferase, mitochondrial; COQ2 homolog; hCOQ2; Para-hydroxybenzoate--polyprenyltransferase; PHB:polyprenyltransferase
Immunogen :A synthetic peptide encompassing a sequence within the center region of human COQ2.
Modification :Unmodification
