Product Name :ASB1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Ankyrin repeat and SOCS box protein 1: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . Mediates Notch-induced ubiquitination and degradation of TCF3/E2A and JAK2 . Functions as a tumor suppressor by enhancing CHCHD3 'Lys-48'-linked ubiquitination, leading to inhibition of the CHCHD3/ROS signaling pathway . Suppresses TAB2-linked 'Lys-48' polyubiquitination and consequently facilitates the initiation of NF-kappa-B and MAPK signaling cascades . May play a role in testis development (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ASB1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA1146; Ankyrin repeat and SOCS box protein 1; ASB-1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ASB1.
Modification :Unmodification
