Product Name :RABGEF1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Rab5 GDP/GTP exchange factor: Acts as a guanine-nucleotide releasing factor (GEF) for RAB5A by promoting the conversion of inactive RAB-GDP to the active form RAB-GTP . Forms a complex with RABEP1 that acts as Rab4/Rab5 effector regulating endosome fusion. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes . Also functions as a ubiquitin ligase (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RABGEF1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RABEX5; Rab5 GDP/GTP exchange factor; RAP1; Rabaptin-5-associated exchange factor for Rab5; Rabex-5
Immunogen :A synthetic peptide encompassing a sequence within the center region of human RABGEF1.
Modification :Unmodification
