Product Name :DHX16 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16: Required for pre-mRNA splicing as a component of the spliceosome . Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). Also plays a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA . Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DHX16 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DBP2; DDX16; KIAA0577; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; ATP-dependent RNA helicase 3; DEAH-box protein 16
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DHX16.
Modification :Unmodification
