Product Name :LRR1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Leucine-rich repeat protein 1: Substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (By similarity). May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of LRR1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PPIL5; Leucine-rich repeat protein 1; 4-1BB-mediated-signaling molecule; 4-1BBlrr; LRR-repeat protein 1; LRR-1; Peptidylprolyl isomerase-like 5
Immunogen :A synthetic peptide encompassing a sequence within the center region of human LRR1.
Modification :Unmodification
