Product Name :TMEM63B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Mechanosensitive cation channel with low conductance and high activation threshold . Osmosensitive cation channel preferentially activated by hypotonic stress . Also acts as a phospholipid scramblase in response to changes in membrane structure: upon changes in membrane curvature and thickness, alters its conformation and translocates phospholipids, such as phosphatidylcholine and sphingomyelin, thereby controlling plasma membrane lipid distribution . Forms a heterodimer with SLC19A2, which mediates phospholipid scramblase activity following Ca(2+) stimulation (By similarity). Expressed in excitatory neurons of the subfornical organ and functions as a thirst receptor that mediates neuronal response to hyperosmolality to drive thirst and drinking behavior (By similarity). Facilitates intestinal motility by promoting proliferation of intestinal stem cells (By similarity). Essential for...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TMEM63B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C6orf110; Transmembrane protein 63B
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TMEM63B.
Modification :Unmodification
