Product Name :RNF183 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :E3 ubiquitin-protein ligase RNF183: Acts as an E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins . Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 . May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling . Mediates the ubiquitination and subsequent lysosomal degradation of ATP1B1 (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RNF183 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RING finger protein 183
Immunogen :A synthetic peptide encompassing a sequence within the center region of human RNF183.
Modification :Unmodification
