Product Name :DACT2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Dapper homolog 2: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DACT2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C6orf116; Dapper homolog 2; Dapper antagonist of catenin 2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human DACT2.
Modification :Unmodification
