Product Name :ZER1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Protein zer-1 homolog: Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC . Acts to target substrates bearing N-terminal degrons for proteasomal degradation with the first four residues of substrates being the key recognition elements . Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N-myristoylation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ZER1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C9orf60; ZYG; ZYG11BL; Protein zer-1 homolog; Hzyg; Zyg-11 homolog B-like protein
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ZER1.
Modification :Unmodification
