Product Name :SLC35D1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Nucleotide sugar transporter SLC35D1: Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for either their cognate nucleoside monophosphate or another nucleotide sugar . Transports various UDP-sugars including UDP-N-acetyl-alpha-D-glucosamine (UDP-GlcNAc), UDP-N-acetyl-alpha-D-galactosamine (UDP-GalNAc) and UDP-alpha-D-glucuronate (UDP-GlcA), which are used by ER glucosyltransferases as sugar donors for the synthesis of sugar chains of glycoproteins, glycolipids and oligosaccharides . May couple UDP-GlcNAc or UDP-GalNAc efflux to UDP-GlcA influx into the ER lumen that in turn stimulates glucuronidation and subsequent excretion of endobiotics and xenobiotics . Plays a role in chondroitin sulfate biosynthesis, which is important for formation of cartilage extracellular matrix and normal skeletal development (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SLC35D1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0260; UGTREL7; UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UDP-GlcA/UDP-GalNAc transporter; Solute carrier family 35 member D1; UDP-galactose transporter-related protein 7; UGTrel7
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SLC35D1.
Modification :Unmodification
