Product Name :GPR137B polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Integral membrane protein GPR137B: Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids . Interacts with Rag GTPases and increases the lysosomal localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome . Involved in the regulation of lysosomal morphology and autophagy
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of GPR137B protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :TM7SF1; Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human GPR137B.
Modification :Unmodification