Product Name :MFSD8 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Major facilitator superfamily domain-containing protein 8: Outward-rectifying chloride channel involved in endolysosomal chloride homeostasis, membrane fusion and function. Conducts chloride currents up to hundreds of picoamperes. Regulates lysosomal calcium content by reducing the lysosomal membrane potential, thereby activating TRPML1 channel and further release of lysosomal calcium ions. Regulates the pH in endolysosomal compartments and may contribute to progressive acidification from endosome to lysosome. Permeable to other halides such as iodide and fluoride ions
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of MFSD8 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CLN7; Major facilitator superfamily domain-containing protein 8; Ceroid-lipofuscinosis neuronal protein 7
Immunogen :A synthetic peptide encompassing a sequence within the center region of human MFSD8.
Modification :Unmodification
