Product Name :SPRED1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Sprouty-related, EVH1 domain-containing protein 1: Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). Negatively regulates hematopoiesis of bone marrow (By similarity). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Attenuates actin stress fiber formation via inhibition of TESK1-mediated phosphorylation of cofilin . Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SPRED1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Sprouty-related, EVH1 domain-containing protein 1; Spred-1; hSpred1
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SPRED1.
Modification :Unmodification