Product Name :KLRF1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Killer cell lectin-like receptor subfamily F member 1: Functions as an activating receptor involved in immunosurveillance upon binding to various ligands displayed at the surface of myeloid cells. Upon interaction with CLEC2B ligand, stimulates NK-cell cytotoxicity and cytokine production leading to the cytolysis of malignant CLEC2B-expressing myeloid cells. Actviation of the common cytotoxicity pathway involves SRC and SYK kinases
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of KLRF1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CLEC5C; ML; Killer cell lectin-like receptor subfamily F member 1; Lectin-like receptor F1; Activating coreceptor NKp80; C-type lectin domain family 5 member C
Immunogen :A synthetic peptide encompassing a sequence within the center region of human KLRF1.
Modification :Unmodification