Product Name :ESRP2 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Epithelial splicing regulatory protein 2: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ESRP2 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RBM35B; Epithelial splicing regulatory protein 2; RNA-binding motif protein 35B; RNA-binding protein 35B
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ESRP2.
Modification :Unmodification
