Product Name :DUSP26 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Dual specificity protein phosphatase 26: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of DUSP26 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DUSP24; LDP4; MKP8; NATA1; SKRP3; Dual specificity protein phosphatase 26; Dual specificity phosphatase SKRP3; Low-molecular-mass dual-specificity phosphatase 4; DSP-4; LDP-4; Mitogen-activated protein kinase phosphatase 8; MAP kinase phosphatase 8; MKP-8; Novel amplified gene in thyroid anaplastic cancer
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human DUSP26.
Modification :Unmodification