Product Name :ZBTB18 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Zinc finger and BTB domain-containing protein 18: Transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. Plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. May also play a role in the organization of chromosomes in the nucleus
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ZBTB18 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RP58; TAZ1; ZNF238; Zinc finger and BTB domain-containing protein 18; 58 kDa repressor protein; Transcriptional repressor RP58; Translin-associated zinc finger protein 1; TAZ-1; Zinc finger protein 238; Zinc finger protein C2H2-171
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ZBTB18.
Modification :Unmodification
