Product Name :TCF15 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Transcription factor 15: Early transcription factor that plays a key role in somitogenesis, paraxial mesoderm development and regulation of stem cell pluripotency. Essential for the mesenchymal to epithelial transition associated with somite formation. Required for somite morphogenesis, thereby regulating patterning of the axial skeleton and skeletal muscles. Required for proper localization of somite epithelium markers during the mesenchymal to epithelial transition. Also plays a key role in regulation of stem cell pluripotency. Promotes pluripotency exit of embryonic stem cells (ESCs) by priming ESCs for differentiation. Acts as a key regulator of self-renewal of hematopoietic stem cells (HSCs) by mediating HSCs quiescence and long-term self-renewal. Together with MEOX2, regulates transcription in heart endothelial cells to regulate fatty acid transport across heart endothelial cells. Acts by forming a hete...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of TCF15 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :BHLHA40; BHLHEC2; Transcription factor 15; TCF-15; Class A basic helix-loop-helix protein 40; bHLHa40; Paraxis; Protein bHLH-EC2
Immunogen :A synthetic peptide encompassing a sequence within the center region of human TCF15.
Modification :Unmodification
