Product Name :ARHGEF15 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Rho guanine nucleotide exchange factor 15: Guanine nucleotide exchange factor (GEF) that activates RhoA, playing a role in the regulation of actin cytoskeleton organization . Is involved in the regulation of vascular smooth muscle contractility . Additionally, it negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2 (By similarity). Does not activate RAC1 or CDC42
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ARHGEF15 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0915; Rho guanine nucleotide exchange factor 15; Ephexin-5; E5; Vsm-RhoGEF
Immunogen :A synthetic peptide encompassing a sequence within the center region of human ARHGEF15.
Modification :Unmodification
