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PTPRB polyclonal antibody

货号: BS33044

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS33044

Product Name :PTPRB polyclonal antibody

Swiss-Prot :P23467

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Receptor-type tyrosine-protein phosphatase beta: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PTPRB protein

BiowMW :~224 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTPB; Receptor-type tyrosine-protein phosphatase beta; Protein-tyrosine phosphatase beta; R-PTP-beta; Vascular endothelial protein tyrosine phosphatase; VE-PTP

Immunogen :A synthetic peptide encompassing a sequence within the center region of human PTPRB.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD27BP expression in SW620 (A) whole cell lysates.