Product Name :RAB43 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Ras-related protein Rab-43: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion . Involved in retrograde transport from the endocytic pathway to the Golgi apparatus . Required for the structural integrity of the Golgi complex . Also controls the anterograde ER-to-Golgi transport of nascent G protein-coupled receptors (including ADRA2A, ADRA2B, ADRA2C, ADRA1B, ADRB2 and AGTR1) and regulates the ER sorting of GPCR members by virtue of its ability to interact directly . Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network . Plays a role in the ma...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RAB43 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :RAB41; Ras-related protein Rab-43; Ras-related protein Rab-41
Immunogen :A synthetic peptide encompassing a sequence within the center region of human RAB43.
Modification :Unmodification
