Product Name :RAB32 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Ras-related protein Rab-32: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes . Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion . Also acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission . Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis . Plays an important role in the control of melanin production and melanosome biogenesis . In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanos...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of RAB32 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Ras-related protein Rab-32
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human RAB32.
Modification :Unmodification
