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KCNE3 polyclonal antibody

货号: BS33022

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS33022

Product Name :KCNE3 polyclonal antibody

Swiss-Prot :Q9Y6H6

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Potassium voltage-gated channel subfamily E member 3: Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE3 beta subunit modulates the gating kinetics and enhances stability of the channel complex . Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit . Associates with KCNC4/Kv3.4 alpha subunit to form the subthreshold Kv channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells . Association with KCNQ1/KCLQT1 alpha subunit may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KCNE3 protein

BiowMW :~11.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Potassium voltage-gated channel subfamily E member 3; MinK-related peptide 2; Minimum potassium ion channel-related peptide 2; Potassium channel subunit beta MiRP2

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human KCNE3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CREB expression in A431 (A), NIH3T3 (B) whole cell lysates.