Product Name :MDFIC polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :MyoD family inhibitor domain-containing protein: Required to control the activity of various transcription factors through their sequestration in the cytoplasm. Retains nuclear Zic proteins ZIC1, ZIC2 and ZIC3 in the cytoplasm and inhibits their transcriptional activation (By similarity). Modulates the expression from cellular promoters. Binds to the axin complex, resulting in an increase in the level of free beta-catenin . Affects axin regulation of the WNT and JNK signaling pathways . Involved in the development of lymphatic vessel valves (By similarity). Required to promote lymphatic endothelial cell migration, in a process that involves down-regulation of integrin beta 1 activation and control of cell adhesion to the extracellular matrix . Regulates the activity of mechanosensitive Piezo channel
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of MDFIC protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MyoD family inhibitor domain-containing protein; I-mfa domain-containing protein; hIC
Immunogen :A synthetic peptide encompassing a sequence within the center region of human MDFIC.
Modification :Unmodification
