Product Name :EDEM3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :ER degradation-enhancing alpha-mannosidase-like protein 3: Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans . May also participate in mannose trimming from all glycoproteins and not just misfolded ones targeted to ERAD . May have alpha 1,2-mannosidase activity (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of EDEM3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C1orf22; ER degradation-enhancing alpha-mannosidase-like protein 3; Alpha-1,2-mannosidase EDEM3
Immunogen :A synthetic peptide encompassing a sequence within the center region of human EDEM3.
Modification :Unmodification
