Product Name :HECW1 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of HECW1 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA0322; NEDL1; E3 ubiquitin-protein ligase HECW1; HECT, C2 and WW domain-containing protein 1; NEDD4-like E3 ubiquitin-protein ligase 1; hNEDL1
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human HECW1.
Modification :Unmodification
