Product Name :NCAPD3 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Condensin-2 complex subunit D3: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis . May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of NCAPD3 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :CAPD3; KIAA0056; Condensin-2 complex subunit D3; Non-SMC condensin II complex subunit D3; hCAP-D3
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human NCAPD3.
Modification :Unmodification
