Product Name :ARPP19 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :cAMP-regulated phosphoprotein 19: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) . Inhibition of PP2A is enhanced when ARPP19 is phosphorylated . When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . May indirectly enhance GAP-43 expression (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of ARPP19 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :cAMP-regulated phosphoprotein 19; ARPP-19
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human ARPP19.
Modification :Unmodification
