Product Name :SLC7A10 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB (1/500 - 1/1000)
Background :Asc-type amino acid transporter 1: Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. Preferentially mediates exchange transport, but can also operate via facilitated diffusion (By similarity) . Acts as a major transporter for glycine, L- and D-serine in the central nervous system. At the spinal cord and brainstem regulates glycine metabolism and glycinergic inhibitory neurotransmission by providing for glycine de novo synthesis from L-serine and glycine recycling from astrocytes to glycinergic motor neurons (By similarity). At Schaffer collateral-CA1 synapses mediates D-serine and glycine release that modulates post-synaptic activation of NMDA receptors and excitatory glutamatergic transmission (By similarity). May regulate D-serine release from mesenchymal progenitors located in developing subcutaneous adipose tissue...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of SLC7A10 protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ASC1; Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10
Immunogen :A synthetic peptide encompassing a sequence within the center region of human SLC7A10.
Modification :Unmodification
