Product Name :MBIP polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :MAP3K12-binding inhibitory protein 1: Functions as part of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 . Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway . Together with MOCS2B, inhibits the activity of stress kinase EIF2AK2/PKR; this may lead to effects such as suppression of JNK activation and subsequent stress-responsive transcription, or suppression of eIF2a phosphorylation to favor translation
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of MBIP protein
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MAP3K12-binding inhibitory protein 1; MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human MBIP.
Modification :Unmodification