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SERINC5 polyclonal antibody

货号: BS32835

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32835

Product Name :SERINC5 polyclonal antibody

Swiss-Prot :Q86VE9

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Serine incorporator 5: Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm . Non-ATP-dependent, non-specific lipid transporter for phosphatidylserine, phosphatidylcholine, and phosphatidylethanolamine. Functions as a scramblase that flips lipids in both directions across the membrane. Phospholipid scrambling results in HIV-1 surface exposure of phosphatidylserine and loss of membrane asymmetry, which leads to changes in HIV-1 Env conformation and loss of infectivity . Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SERINC5 protein.

BiowMW :~47.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C5orf12; Serine incorporator 5

Immunogen :A synthetic peptide encompassing a sequence within the center region of human SERINC5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Glucagon expression in HepG2 (A), HT29 (B) whole cell lysates.

免疫沉淀（IP）