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becn1 polyclonal antibody

货号: BS32809

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32809

Product Name :becn1 polyclonal antibody

Swiss-Prot :A2A135

Host :Rabbit

Reactivity :Zebrafish

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Beclin-1: Plays a central role in autophagy . Acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2 . Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis . May play a role in antiviral host defense

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of becn1 protein.

BiowMW :~51.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Immunogen :A synthetic peptide encompassing a sequence within the Central region of zebrafish becn1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of becn1 expression in Zebrafish (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）