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atg5 polyclonal antibody

货号: BS32800

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS32800

Product Name :atg5 polyclonal antibody

Swiss-Prot :Q6DEM4

Host :Rabbit

Reactivity :Zebrafish

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Autophagy protein 5: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy). Also required for mitophagy, which eliminates defective or superfluous mitochondria in order to fulfill cellular energy requirements and prevent excess ROS production. Conjugation with atg12, through a ubiquitin-like conjugating system involving atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate acts as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity). Has a role in meiosis and sporulation

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of atg5 protein.

BiowMW :~32.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Immunogen :A synthetic peptide encompassing a sequence within the Central region of zebrafish atg5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of KLHL2 expression in 293 (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）